Abstract The tumor microenvironment (TME) is comprised of non-malignant cells that interact with each other and with cancer cells, critically impacting cancer biology.The TME Transmission is complex, and understanding it requires simplifying approaches.Here we provide an experimental-mathematical approach to decompose the TME into small circuits of
The combination of Sintilimab with pemetrexed/platinum has become the first-line treatment for non-squamous non-small-cell lung carcinoma (NSCLC).Here, we report a patient with metastatic large cell neuroendocrine carcinoma (LCNEC) treated with Sintilimab for five cycles who developed shortness of breath after activity.The level of creatine kinase
This study aimed to collectibles develop a set of PISA-like mathematics problems on uncertainty and data content using football as a context which was valid, practical and had potential effects on students’ mathematical literacy ability.The method used in this study is design research with development studies type which had two stage: the prelimi
Onobrychis pindicola subsp.urumovii Degen & Dren.is an endemic with restricted distribution on Pirin Mts.and Slavjanka Mts.(Balkan Peninsula, SW Bulgaria).It is obligatorily dependent upon insect Outdoor Umbrella vectors for pollen transport, being a self-incompatible plant.The aim of this study was: 1) to identify which bumblebees pollinate Onobry